The Hispanic Community Health Study/Study of Latinos Sociocultural Ancillary Study: sample, design, and procedures.

OBJECTIVES The Hispanic Community Health Study/Study of Latinos (HCHS/SOL) Sociocultural Ancillary Study aims to examine associations between sociocultural and psychosocial factors and cardiovascular disease (CVD) and metabolic syndrome prevalence in Hispanics/Latinos. The conceptual framework is based on the Reserve Capacity and Lifespan Biopsychosocial Models, which emphasize multiple risk and protective pathways underlying socioeconomic and ethnic influences in health. This study describes the rationale, participants, and procedures for the HCHS/SOL Sociocultural Ancillary Study. DESIGN AND SETTING The Sociocultural Ancillary Study to the HCHS/SOL is a cross-sectional cohort study with future opportunities for prospective investigation. PARTICIPANTS Participants were 5,313 adults, aged 18-74 years, of self-identified Hispanic/Latino descent and representing multiple Hispanic/Latino background groups, recruited from the Bronx, N.Y., Chicago, Ill., Miami, Fla., and San Diego, Calif. INTERVENTION Participants completed an interview-administered sociocultural assessment battery within 9 months of their HCHS/SOL clinical baseline exam. OUTCOME MEASURES The primary outcomes are CVD and metabolic syndrome and its component risk factors. RESULTS The Sociocultural Ancillary Study sample is broadly representative of the HCHS/SOL cohort. Weighted demographics are: 55% male, 56% 18-44 years, 44% > or =45 years, and 37% Mexican, 20% Cuban, 16% Puerto Rican, 12% Dominican, 8% Central American, and 5% South American descent. CONCLUSIONS By testing theoretically driven hypotheses concerning sociocultural and psychosocial factors in CVD, the Sociocultural Ancillary Study seeks to inform future prevention and intervention efforts for US Hispanic/Latinos.